2010MY Mercedes-Benz GL-Class EPA Fuel Mileage Estimates
| Model | Drivetrain | City | Highway | Combined |
| GL350 BlueTEC 4MATIC | 7-spd Automatic | 17 | 23 | 19 |
| GL450 4MATIC | 7-spd Automatic | 13 | 17 | 14 |
| GL550 4MATIC | 7-spd Automatic | 12 | 17 | 14 |
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