2010MY Mercedes-Benz SLK-Class EPA Fuel Mileage Estimates
| Model | Drivetrain | City | Highway | Combined |
| SLK300 | 6-spd Manual | 17 | 26 | 20 |
| SLK300 | 7-spd Automatic | 19 | 26 | 21 |
| SLK350 | 7-spd Automatic | 18 | 25 | 20 |
| SLK55 AMG | 7-spd Automatic | 14 | 22 | 17 |
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