2010MY Mercedes-Benz CL-Class EPA Fuel Mileage Estimates
| Model | Drivetrain | City | Highway | Combined |
| CL550 4MATIC | 7-spd Automatic | 14 | 21 | 17 |
| CL600 | 5-spd Automatic | 11 | 17 | 14 |
| CL63 AMG | 7-spd Automatic | 11 | 18 | 14 |
| CL65 AMG | 5-spd Automatic | 11 | 17 | 13 |
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